Microreaction & Crystalization


SOPAT   In Line Microscopy 
Particle size distribution and shape analysis  
In almost all cases the quality of a product is dependent of the characteristics of the available particles and their size distribution. SOPAT offers a flexible particle measurement system. It consists of a tailor made SOPAT probe, the innovative SOPAT software, and the SOPAT central box, all of which can be customized to your needs.

Emulsification, crystallization or polymerization processes, our innovative particle measurement technology can be used to analyze a wide range of applications to obtain information on the concentration, size, shape or distribution of particles.

Measurements occur inline during the production process, so neither sampling nor dilution is necessary. This guarantees that the sample is neither changed on the way to the laboratory, nor must production be stopped.


PureNano - Continuous Crystallizer 
As leading pharmaceutical companies continue to explore the benefits of continuous manufacturing and bottom-up nanoparticle creation, Microfluidics' PureNano Continuous Crystallizer is being used to create stabile inhalable formulations, improve the bioavailability of antibiotics and target delivery of novel cancer treatments, among other possibilities.
PureNano is a platform technology with several innovative applications:
  • Continuous crystallization
  • Efficient nanoencapsulation
  • Chemical reactions
  • Process intensification

PureNano (then known as MRT) has been named a Nano50 Award winner due to its unique capabilities to produce superior particle size distributions efficiently for a number of APIs:
Active Pharmaceutical Ingredient PureNano Crystallization 1 pass (nm) Beaker
Crystallization (nm)
Top-down Particle
Size Reduction
25 passes (nm)
Norfloxacin 180 3,000 x 1,000,000 428
Oxcarbazepine 767 5,000 x 20,000 1,200
Loratadine 90 - 332    

Call us for more information

Tetra Sense Scientific Tools Ltd.      Tel:+972 (0)4 6272720,      Fax:+972 (0)4 6272719,      Email: sales@tetrasense.co.il

Address: 19 Bareket St,  POB 3107, Industrial Park (North) Caesarea 3088900, Israel      Website: www.tetrasense.co.il

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